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“How Am I Supposed to Live Without You” is a song originally recorded by Laura Branigan in 1983. The song was recorded later the same decade by its co-writer, Michael Bolton. In 1989, Michael Bolton recorded his own version of the song and it became his biggest hit, reaching number one on both the Billboard Hot 100 and Adult Contemporary charts in 1990. On the Hot 100, the song became the first #1 single of the 1990s. This marked the second time the song had topped the U.S. AC chart. The song appears on his album Soul Provider and on Michael Bolton: Greatest Hits (1985-1995). In the Episode Live and Let Fry from American Dad! the version was featured.

Source: Wikipedia